Calcium-activated hyperpolarizations in rat locus coeruleus neurons in vitro.
نویسندگان
چکیده
منابع مشابه
Local opiate withdrawal in locus coeruleus neurons in vitro.
Noradrenergic neurons of the brain nucleus locus coeruleus (LC) become hyperactive during opiate withdrawal. It has been uncertain to what extent such hyperactivity reflects changes in intrinsic properties of these cells. The effects of withdrawal from chronic morphine on the activity of LC neurons were studied using intracellular recordings in rat brain slices. LC neurons in slices from chroni...
متن کاملInward rectification of resting and opiate-activated potassium currents in rat locus coeruleus neurons.
Intracellular recordings were made from rat locus coeruleus neurons in vitro, and membrane currents were measured at potentials from -50 to -130 mV. In the absence of any applied agonists, the slope conductance of the cells increased 3-fold when the cell was hyperpolarized from -60 to -120 mV. This conductance increase was complete within 5 msec of the onset of a hyperpolarizing command and was...
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Murai, Yoshinaka, Hitoshi Ishibashi, Susumu Koyama, and role of [Ca]i in ischemic neurotoxicity is supported by the Norio Akaike. Ca-activated K currents in rat locus coeruleus fact that removal of Ca from the extracellular fluid during neurons induced by experimental ischemia, anoxia, and hypoglyceischemia or the blockage of glutamate receptors prevented mia. J. Neurophysiol. 78: 2674–2681, 19...
متن کاملCa2+-activated K+ currents in rat locus coeruleus neurons induced by experimental ischemia, anoxia, and hypoglycemia.
Ca2+-activated K+ currents in rat locus coeruleus neurons induced by experimental ischemia, anoxia, and hypoglycemia. J. Neurophysiol. 78: 2674-2681, 1997. The effects of metabolic inhibition on membrane currents and N-methyl--aspartic acid (NMDA)-induced currents were investigated in dissociated rat locus coeruleus (LC) neurons by using the nystatin perforated patch recording mode under voltag...
متن کاملOmega-conotoxin prevents myelin-evoked growth cone collapse in neonatal rat locus coeruleus neurons in vitro.
The response of neonatal rat locus coeruleus neurons to contact with myelin extracts prepared from the CNS and PNS was examined. The growth cones of these neurons collapsed following contact with central myelin, but continued to elongate on contact with peripheral myelin. Central myelin elicited an increase in the intracellular free calcium concentration in these growth cones, while peripheral ...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1993
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1993.sp019806